The Drive to Discover. The Experience to Deliver.

Careers At Incyte Corporation

Looking for a challenge and a chance to grow your career?

Then Incyte is the pharmaceutical company for you. While our pipeline demonstrates the ability to compete with much larger pharmaceutical companies in selecting compelling targets and creating high-quality drug candidates, our smaller size enables employees to see the direct impact of their contributions on the direction of the company. Due to our smart, agile culture and cutting-edge science, we delivered a novel, first-to-market product in an unmet medical need in 2011 - the first in the company's history.

Opportunities for taking on new and/or additional responsibilities, in addition to advancement, are a key element in our culture. Add to that a science-based, fast-paced work environment and you’ve got an exciting company in which to work.

In addition to opportunities for growth, we offer an outstanding benefits andcompensation package to help meet personal needs as well.

Take a look at our current openings to find the match that’s right for you!

Incyte Corporation values the talents of our diverse workforce and is proud to be an Equal Opportunity Employer.

Sr. Research Investigator / Principal Investigator, Antibody Pharmacology

Department: Preclinical Pharmacology
Location: Incyte Corporate Headquarters

Sr. Research Investigator / Principal Investigator, Antibody Pharmacology

This individual will work as part of the antibody pharmacology team focusing on immune-based in vitro assays focused on target validation and characterization of therapeutic leads. A successful candidate will be able to design and utilize the appropriate preclinical studies to provide pharmacological insight into drug mechanism of action. The candidate should also have experience in developing in vitro assays and a deep knowledge of technologies commonly used to assess immune endpoints. Participation in small molecule discovery may be possible.

Job Responsibilities: 

  • Identify, design, and utilize the appropriate in vitro model systems to address key biological or pharmacological questions

  • Design of in vitro experiments to determine the functional effect(s) of candidate target activation/inhibition by using a variety of assays to interrogate immune end-points

  • Collaborate with other functional groups within drug discovery to achieve key goals

  • Research potential new antibody/small molecule targets and present to management for consideration as early discovery programs

  • Effectively coordinate with CRO or external collaboration to evaluate potential clinical candidates

  • Generate written reports and PowerPoint presentations

Minimum Requirements: 

  • Ph.D. in Immunology, Cancer Biology, Pharmacology or related field

  • 1-3 years of post-doctoral experience in a relevant field

  • Strong background in multi-parameter flow cytometry

  • Expertise in a variety of immunological functional and molecular assays

  • Excellent oral and written communication skills and a solid publication record

  • Extensive in vitro experience required

  • Pharmaceutical or biotech experience preferred, but not required


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