The Drive to Discover. The Experience to Deliver.

Careers At Incyte Corporation

Looking for a challenge and a chance to grow your career?

Then Incyte is the pharmaceutical company for you. While our pipeline demonstrates the ability to compete with much larger pharmaceutical companies in selecting compelling targets and creating high-quality drug candidates, our smaller size enables employees to see the direct impact of their contributions on the direction of the company. Due to our smart, agile culture and cutting-edge science, we delivered a novel, first-to-market product in an unmet medical need in 2011 - the first in the company's history.

Opportunities for taking on new and/or additional responsibilities, in addition to advancement, are a key element in our culture. Add to that a science-based, fast-paced work environment and you’ve got an exciting company in which to work.

In addition to opportunities for growth, we offer an outstanding benefits andcompensation package to help meet personal needs as well.

Take a look at our current openings to find the match that’s right for you!

Incyte Corporation values the talents of our diverse workforce and is proud to be an Equal Opportunity Employer.

Research Investigator, Chemistry (Computational)

Department: Discovery Chemistry
Location: Incyte Corporate Headquarters

Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value. 

The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.

Job Summary:
The Research Scientist in Chemistry (Computational) will will be responsible for cheminformatics and structure based design to support small molecule drug discovery

Job Responsibilities:

  • Develop and maintain in-house written cheminformatics software for datamining and automation.
  • Apply structure and ligand-based design strategies to evaluate and improve potency of lead compounds.
  • Collaborate with project team members to analyze and visualize scientific data.


  • PhD in computational chemistry is required. Post-doctoral experience is preferred.
  • Proficiency in scientific programming with an understanding of software development life-cycle is essential.
  • Experience with VB.NET/C#, JavaScript, Python or Java is required.
  • Experience with Schrodinger or MOE molecular modelling suites is required.
  • Experience with KNIME, RDKit, Indigo or other cheminformatics platforms is preferred.
  • Experience in database management is preferred.
  • Experience in molecular dynamics and free energy perturbation calculations is desirable.
  • Excellent communication skills and the ability to work well with the chemistry team are essential.
  • A strong track record of academic and scientific achievement is required.

Disclaimer:  The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications.   Management reserves the right to change or modify such duties as required.

Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.

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